The crisis is centred around the restive eastern city of Beni in North Kivu, a region which has been blighted by armed conflict which has hampered efforts to curb the outbreak.
And, the U.S. State Department issued a "do not travel" alert because of armed group activity and major outbreaks of violence targeting civilians.
Seven United Nations peacekeepers were killed in one such skirmish earlier this month, and another 11 civilians - including two Congolese health workers - were killed in the region last month.
So far this outbreak declared on August 1, has 198 confirmed deaths, with another 47 probable ones, Congo's health ministry said.
This clinical trial is the first-ever multi-drug trial for an Ebola treatment.
At least 245 people have died from the Ebola virus in the Democratic Republic of Congo in recent weeks, the country's health ministry said Thursday, making it the second-deadliest outbreak of the disease in history. Dozens of rebel groups are active and attacks by them have forced workers to halt Ebola containment for days at a time.
G20 Summit: May 'encourages' Saudi Arabia to co-operate in murder investigation
In a video posted by the Saudi Gazette newspaper the two leaders can be seen speaking in hushed tones with their heads close together.
North Kivu and Ituri are among the most populous provinces in the Democratic Republic of the Congo and share borders with Rwanda, Uganda and South Sudan.
Malaria can normally be diagnosed with a rapid blood test, but the risk of Ebola transmission means health workers have to rely on an assessment of symptoms, he said. "These trials will contribute to building that knowledge, while we continue to respond on every front to bring the current outbreak to an end".
Some 38 people died after they had a hemorrhagic fever, but it couldn't be verified whether they died of Ebola because they were buried without an autopsy. There is also a reluctance among some residents to seek care or allow health workers to vaccinate, conduct contact tracing and perform safe burials, according to health officials.
'No other epidemic in the world has been as complex as the one we are now experiencing, ' said Dr Oly Ilunga Kalenga, the DRC's health minister.
Explaining the World Health Organization-backed initiative, WHO Director-General Dr Tedros Adhanom Ghebreyesus said "randomised control trial" in DR Congo was a "giant step" that would "bring clarity about what works best, and save many lives in years to come". "Is there potential for requiring global response?"
Ebola has, in the meantime, killed 241 people, the ministry said in a statement late Tuesday.