During a, to discuss "potential cooperation between American tech companies and Saudi Arabia", the prince did away with his traditional white robes as he met with executives and investors.
"The Kingdom affirms its total rejection of any threats and attempts to undermine it, whether by threatening to impose economic sanctions, using political pressures, or repeating false accusations that will not undermine the Kingdom and its staunch positions and Arab, Islamic and global status", the ministry added.
The de-facto ruler of the Gulf kingdom, who is next in line to be king, is cited in the reports as holding an interest in purchasing the historic sporting institution to give his ruling family an investment to rival those of the Abu Dhabi-ruling owners of Manchester City and the Qatari-backed Paris Saint Germain.
"You are talking about a geopolitical situation becoming even worse and Saudi Arabia is going to show its stubborn attitude again", Naeem Aslam, chief market analyst at Think Markets UK in London, told Bloomberg.
The Saudi warnings came after the country's stock market fell as much as 7% on Sunday amid fears of sanctions.
"Germany, the United Kingdom and France share the grave concern expressed by others including HRVP [Federica] Mogherini and UNSG [Antonio] Guterres, and are treating this incident with the utmost seriousness".
Outbreak of mysterious polio-like disease plagues residents in 22 states
What is known about the illness is that more than 90 percent of the confirmed cases are in children 18 years old or younger. Todd Ellerin, director of infectious diseases at South Shore Hospital in Weymouth, told ABC News in an interview.
'There needs to be a credible investigation to establish the truth about what happened, and - if relevant - to identify those bearing responsibility for the disappearance of Jamal Khashoggi, and ensure that they are held to account.
But top business leaders are now distancing themselves from the Saudi government.
The CEO of the us bank JP Morgan has already announced that he wouldn't make it the "Davos of the desert" and several media outlets, including the Financial Times, the New York Times, The Economist, Bloomberg and CNN have made a decision to snub this event. "From where we sit, we don't see any demand for Saudi equities at all".
Turkish authorities believe 15 Saudi men who arrived in Istanbul on October 2 were connected to Khashoggi's disappearance and possible killing. Executivesincluding JPMorgan Chase (JPM) CEO Jamie Dimon have pulled out of an investment conference taking place in the kingdom later this month. According to Turkey, he was then tortured, killed and dismembered.
Still, regional traders said speculation the Khashoggi case might deter some inflows of foreign investment - and that a backlash in the US Congress could lead to US sanctions against some Saudi individuals - had triggered panic selling of stocks by some local investors.